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Search Results for " pparα agonist 1 "

16

Compounds

Cat No. Product Name Synonyms Targets
T62266 PPARα agonist 1
PPARα agonist 1 is a complete and potent PPARα agonist.
T62968 PPARαagonist 1
PPARαagonist 1 is a potent PPARα/PPARδ dual agonist with EC50 values of 7.0 nM for PPARα and 8.4 nM for PPARδ. PPARαagonist 1 exhibits high selectivity for PPARγ (EC50: 1316.1 nM). agonist 1 has potential for non-a...
T60535 PPARαagonist 1
PPARαagonist 1 is a potent and dual PPARα/γ partial agonist which is a promising prototype for the research of dyslipidemia and diabetes. PPARαagonist 1 has EC50 values of 28 nM and 69 nM for PPARα and PPARγ, respe...
TQ0107 Pemafibrate (R)-K-13675 PPAR
Pemafibrate ((R)-K-13675) is a highly specific PPARα agonist (EC50: 1 nM).
T6524 GW0742 GW610742 PPAR
GW0742 (GW610742) is an effective and specific PPARδ agonist (EC50: 1 nM/1.1 μM/2 μM, for human PPARδ/α/γ).
T36076 Ciprofibrate impurity A
Ciprofibrate impurity A is an impurity of Ciprofibrate. Ciprofibrate is a PPARα agonist[1]. [1]. Passilly, P., et al., Phosphorylation of peroxisome proliferator-activated receptor alpha in rat Fao cells and stimulation ...
T15243 Ertiprotafib PTP 112 Phosphatase , PPAR
Ertiprotafib is a PTP1B, IkB kinase β (IKK-β), and a dual PPARα and PPARβ agonist inhibitor ( IC50s: 1.6 μM for PTP1B, 400 nM for IKK-β, an EC50 of ~1 μM for PPARα/PPARβ).
T75690 Wistin
Wistin, isolated from Caragana sinica roots, is a PPARα and PPARγ agonist [1] [2] .
TMIH-0422 Pemafibrate-d7
Pemafibrate-d7 is a deuterated compound of Pemafibrate. Pemafibrate has a CAS number of 848259-27-8. Pemafibrate is a highly specific PPARα agonist (EC50: 1 nM).
T35800 MD001
MD001 is a dual agonist of peroxisome proliferator-activated receptor α (PPARα) and PPARγ.1 It binds to PPARα and PPARγ (Kds = 9.55 and 0.14 μM, respectively) but does not bind to PPARβ/δ at concentrations up to 500 μM. ...
T37414 CAY10771
CAY10771 is a dual agonist of farnesoid X receptor (FXR) and peroxisome proliferator-activated receptor δ (PPARδ).1It activates FXR and PPARδ in reporter assays using HEK293T cells (EC50s = 0.94 and 1.5 μM, respectively)...
T21812 LT175
LT175, a dual PPARα/γ ligand, demonstrates potent insulin-sensitizing effects while exhibiting reduced adipogenic properties. This compound is an orally active partial agonist targeting PPARγ, with EC50 values of 0.22 μm...
T35799 MBX-8025 (sodium salt)
MBX-8025 is an agonist of peroxisome proliferator-activated receptor δ (PPARδ).1 It is greater than 750- and 2,500-fold selective for PPARδ over PPARα and PPARγ. MBX-8025 (10 mg/kg per day for eight weeks) reduces increa...
T35816 ZLY032
ZLY032 is a dual agonist of free fatty acid receptor 1 (FFAR1/GPR40; EC50= 68 nM in a FLIPR assay) and peroxisome proliferator-activated receptor δ (PPARδ; EC50= 102 nM in a reporter assay).1It is selective for FFAR1 and...
T14216 AMG 837 Others
AMG 837 is a partial GPR40 agonist with an EC50 value of 13 nM, showcasing 85% of the maximal activity displayed by DHA in standard assay conditions, indicating its high potency and selectivity in vitro. This compound ex...
T83765 Dendrogenin A ​DDA
Dendrogenin A (DDA) is a compound acting as a selective liver X receptor (LXR) modulator, cholesterol epoxide hydrolase inhibitor (Ki = 120 nM), and a metabolic product of cholesterol, originating from 5,6α-epoxy cholest...
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